BioLASCO Taiwan Co., Ltd. - uses Charles River Laboratories (CRL)
technology "IGS Breeding System" to breed VAF/plus®
(virus antibody free) animals and to manage CRL laboratory animals.
This is to ensure that, whether customers buy CRL animals in any
other Charles River locations, the animals will be bred with
uniformity. IGS (International Genetic System) serves to stabilise
the genetic diversity that inherently exists in production colonies,
and to standardise this diversity between production colonies
worldwide.
VAF/plus®
(SPF) Laboratory Rodents Available

Outbred Rats
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Nomenclature Crl: CD®
(SD) IGS. BR
Origin originated in 1925 by Robert W. Dawley from a hybrid
hooded male and a female Wistar rat. To CRL in 1950 from
Sprague Dawley, Inc. In 1991, 8 colonies were selected to
form the IGS foundation colony. Rederived into isolator
foundation colony in 1997. IGS refers to animals bred using
the CRL international Genetic Standard System. To BioLASCO
Taiwan in 2004 from CRL. Coat color White (albino). |

Outbred Rats |
Nomenclature Crl: (WI).
BR Origin To
Scientific Products Farm, Ltd. Predecessor of Charles River
United Kingdom (CRL UK) in 1947 from Wistar Institute. To
CRL in 1975 from CRL UK. This particular colony was selected
because of a low incidence of hydronephrosis. To BioLASCO
Taiwan in 2004 from CRL. Coat color White (albino). |

Inbred Mice |
Nomenclature Crl: CD-1®
(ICR). BR Origin The original group of Swiss that
served as progenitors of this stock consisted of two male
and seven female albino mice derived from a non-inbred stock
in the laboratory of Dr. De Coulon, Centre Anticancereux
Romand, Lausanne, Switzerland. These animals were imported
into the United States by Dr. Clara Lynch of the Rockefeller
Institute in 1926. The Hauschka Ha/ICR stock was initiated
in 1948 at the Institute for Cancer Research in Philadelphia
from "Swiss" mice of Rockefeller origin. To Dr. Edward
Mirand of Roswell Park memorial institute where they were
designated as HaM/ICR. To CRL in 1959. To BioLASCO Taiwan in
2004 from CRL. Coat color White (albino). |

Outbred Mice |
Nomenclature Crl: BALB/cAnN.
BR Origin H. J. Bagg developed the "Bagg albino" in 1913
from stock from an Ohio pet dealer. Inbred in 1923 by
McDowell. To Snell in 1932 at F26, to andervont in 1935. To
NIH 1952 from Andervont at F72. To CRL in 1974 from NIH. To
BioLASCO Taiwan in 2004 from CRL. Coat color White
(albino). |

Inbred Mice |
Nomenclature Crl: C57BL/6N.
BR Origin
Developed by C. C. Little in 1921, from a mating of Miss
Abby Lathrop's stock that also gave rise to strains C57BR
and C57L. Strains 6 and 10 separated about 1937. To Jackson
Laboratories in 1948 from Hall. To NIH in 1951 from Jackson
Laboratories at F32. To CRL in 1974 from NIH. To BioLASCO
Taiwan in 2004. Coat color Black. |

Inbred Mice |
Nomenclature Crl: C3H/HeN.
BR Origin From
a cross of a Bagg albino female and DBA male by Strong in
1920. A Litter of 4 females and 2 males sent to Andervontin
1930, then to Heston at F35. To NIH in 1951 from Heston at
F57. To CRL in 1974 from NIH. To BioLASCO in 2004 from CRL.
Coat color Agouti (wild type). |

Inbred Mice |
Nomenclature Crl: DBA/2N.
BR Origin
Developed by C. C. Little in 1909 from stock segrating for
coat color. Oldest of all the inbred strains of mice. In
1929-1930 crosses were made between sublines, and several
new sublines were established, including the widely used
sublines 1 (previously called 12) and 2 (previously called
212). To Mider in 1938. To NIH in 1951 from Mider at F34. To
CRL in 1974 from NIH. To BioLASCO Taiwan in 2004 from CRL.
Coat color Non-Agouti (dilute brown). |
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