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  • HOME
  • ABOUT US
  • REAGENTS
    • i-DNA Brand
    • Other Brands
  • SERVICES
    • Antibody Purification Service
    • Bacterial E.coli Competent Cell Preparation
    • Custom Peptide Synthesis
    • Custom-Made Monoclonal Antibody
    • Custom-Made Polyclonal Antibody
      • Rabbit Polyclonal Antisera Against PEPTIDE
      • Rabbit Polyclonal Antisera Against PROTEIN
    • DNA Paternity Testing
    • DNA Purification
    • ELISA
    • Gene Synthesis
    • Laboratory Animal Diagnostic
      • Comprehensive Health Monitoring For Rat & Mouse
      • Infectious Disease PCR Testing For Rat & Mouse
      • Mouse and Rat Serology Testing by MFIA
      • Custom Animal Serum, Whole Blood and Plasma
    • Preparation of Custom Buffers and Solutions
    • Protein Profiling
      • Protein Profiling Service for Cytokines
      • Disease-Specific Protein Profiling Service
      • Protein Profiling Service For Transcriptional Factors
    • GST- or His Taq Protein Purification Service
    • RNA Gene Expression
      • RNA Gene Expression For Multiplex
      • RNA Gene Expression For Single Plex
    • Site-Directed Mutagenesis
    • SNP and Genotyping
    • Subcloning
  • INSTRUMENTS
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Protein Profiling Service For Transcriptional Factors

i-DNA Biotechnology (M) Sdn Bhd > Protein Profiling Service For Transcriptional Factors

Protein Profiling Service For Transcriptional Factors

Protein profiling uses xMAP technology to quantify multiple target proteins simultaneously in the same sample, same well.

Transcription factors (TFs), which play crucial roles in the regulation of gene expression in the human genome, are highly regulated by a variety of mechanisms. A single extracellular stimulus can trigger multiple signaling pathways, and these in turn can activate multiple TFs to mediate the inducible expression of target genes. Alterations in the activities of TFs are often associated with human diseases, such as altered activating factor 1, estrogen receptor, and p53 function in cancer, nuclear factor kB in inflammatory diseases, and peroxisome proliferator-activated receptor gamma in obesity. A systematic assay for profiling the activation of TFs will aid in elucidating the mechanisms of TF activation, reveal altered TFs associated with human diseases, and aid in developing assays for drug discovery.

i-DNA offers protein profiling service for 85 common transcriptional factors starting from cell or tissue.

  • Species that can recognize are human, mouse and rat.
  • Require as little as 500 ng for whole cell lysate or 250 ng for nuclear extract.
  • Quantitate TF binding activity.
  • Cost effective based on per data point.
  • Fast turnaround within 24 hour.

Please contact us for a no-obligation consultation. All information provided will be kept strictly confidential.

The 85 TFs are divided into 2 panels:

Panel 1

RUNX/AML
ELK1
ISRE
OCT
API
ER
MEF-2
P53
AP2
ETS/PEA
MYOD
PAX3
AR
FAST1
NF-1
PAX5
ATF2
FKHR-1
NFAT
PPAR
BRN3
GATA-1
NF-E1(YY1)
SMAD
CEBP
GR/PR
NF-E2
STAT1
C-MYB
HIF-1
NFkB1
STAT3
CREB
HNF-1
NKX-2.5
STAT4
E2F1
IRF
NF-Y
STAT5
TFIID


Panel 2

EV-1
GAG
IKAROS
HBS/XBP
HAS+HBS
ALF-1/TAL-1
TREF-1/2
EGR
NFkB
c-MYC
Neuro-D1
PDX-1
TR
MRE
ELF-1
SRE
H4TF
HiNF
KPF-1
LF-A1
LvF
MTF
PUR-1
RB
TEF-3
AP-1
USF-1
XRE
GFI-1
NPAS2
PIT-1
SRY
E47
CCAAT
AP-4
CDP
XBP-1
CEF-1
ANTI-RE
COUP-TF
SIE
HSF
TR (DR-4)
TFIID

 

Bacteria E.codiv Competent Cell Preparation
Custom Peptide Synthesis
Custom-Made Monoclonal Antibody
Rabbit Polyclonal Antisera Against PEPTIDE
Rabbit Polyclonal Antisera Against PROTEIN
DNA Paternity Testing
DNA Purification
ELISA
Gene Synthesis
Comprehensive Health Monitoring For Rat & Mouse
Infectious Disease PCR Testing For Rat & Mouse
Mouse and Rat Serology Testing by MFIA
Custom Animal Serum, Whole Blood and Plasma
Preparation of Custom Buffers and Solutions
Protein Profiling Service for Cytokines
Disease-Specific Protein Profiling Service
Protein Profiling Service For Transcriptional Factors
GST-or His Taq Protein Purification Service
RNA Gene Expression For Multiplex
RNA Gene Expression For Single Plex
Site-Directed Mutagenesis
SNP and Genotyping
Subcloning

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i-DNA Biotechnology (M) Sdn Bhd
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58200 Kuala Lumpur.


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f : 03 7987 4566

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